Funded Research
Funded Research, 1990 - 2007
Research Projects 2005 - 2007
Title: Treatment of demyelinating disease by transient gene therapy using cytokine expressing Semliki Forest virus vectors.
Researchers: Atkins, G.J. and Sheehan, B.J.
Duration: 3 years
Title: Endoplasmic reticulum stress as a component of oligodendrocyte degeneration during MS.
Researchers: Conducted by Fitzgerald, McQuaid, Mahon
Duration: 3 years
Title: Fine mapping and assessment of candidate genes for MS suceptibility including 20 loci from the GAMES study and genes for neuropeptides and their receptors.
Researchers: Graham, Vandenbroeck, Hawkins and Hutchinson
Duration: 3 years
Title: Prevalance study of MS in Southwest Ireland
Researchers: Conducted by Dr Jennifer Spencer and Dr Brian Sweeney
Duration: 1 year
Research Projects 1990 - 2005
Project: Neuropsychological Correlates of Chronic Pain in Multiple Sclerosis
Researcher: Dr. Michael Hutchinson, 1990
Duration: One year project
Contact: Dr. Michael Hutchinson, Consultant Neurologist, St Vincents Hospital
Project: The Role of Activated T cells in Multiple Sclerosis
Researcher: Prof. C. Feighery and Dr. M. Hutchinson, 1991
Duration: One year project
Contact: Dr. Michael Hutchinson, Consultant Neurologist, St Vincents Hospital
Project: A Prospective Study of Cognitive Function, Mood Disorder and Disability in a Population of Early Diagnosed Multiple Sclerosis Patients
Researcher: Hutchinson and Hutchinson, 1991-1994
Duration: Three year project
Contact: Dr. Michael Hutchinson, Consultant Neurologist, St Vincents Hospital
Project: Molecular Analysis of the Mechanism of Virus-Induced Demyelination and its Relevance to the Pathogenesis of Multiple Sclerosis
Researcher: Prof. Gregory J. Atkins Ph.D, 1990 – 1993
Duration: Three year project
Contact: Prof. G. Atkins, Dept of Microbiology, Moyne Institute, Trinity College, Dublin
Project: A European Multicentre Prospective Study of the Effects of Pregnancy and the Puerperium in Multiple Sclerosis
Researcher: Dr. Michael Hutchinson, 1993 – 1995
Duration: Two year project
Contact: Dr Michael Hutchinson, Consultant Neurologist, St Vincents Hospital
Project: The Mechanism of Induction of Anti-Myelin Autoimmunity by Viruses and its Relevance to Multiple Sclerosis
Researcher: Prof. G. J. Atkins & Prof. B. J. Sheahan, 1993 – 1996
Duration: Three year project
Contact: Prof. G. Atkins, Dept of Microbiology, Moyne Institute, Trinity College, Dublin
Project: An Analysis of Glial Cell Lineage and Plasticity using Retroviral Lineage Tracing and Transplantation Techniques
Researcher: Dr. K.W. McDermott, 1993 – 1996
Duration: Three year project
Contact:
Project: Analysis of the Mechanism of Virus-Induced Oligodendrocyte Cell Death
Researcher: Prof. G. J. Atkins & Prof. B. J. Sheahan, 1996 - 1999
Duration: Three year project
Contact: Prof. G. J. Atkins, Dept of Microbiology, Moyne Institute, Trinity College
Project: Focus for MS: A Survey of the Utilisation and Perceptions of Health and Community Services by People with Multiple Sclerosis in the W.H.B Region
Researcher: Aidan Larkin, September 1999
Duration: One year project
Contact: Aidan Larkin, Western Regional Office
Project: Investigation of the Co stimulatory Requirements of Myelin-Reactive T Cells in Multiple Sclerosis
Researcher: Dr. A. D. Crockard & Dr S. A. Hawkins, 1999
Duration: One year project
Contact: Dr. Stanley Hawkins, Consultant Neurologist, Institute of Clinical Science, Royal Victoria Hospital, Grosvenor Rd, Belfast BT12
Project: Multiple Sclerosis in Malta
Researcher: Dr. G. K. Dean, 1999
Duration: One year project
Project: Transient Virus Infections in the Etiology of Multiple Sclerosis
Researcher: Prof. G. J. Atkins, Prof B. J. Sheahan, & Dr. M. M. Morris-Downes, 1999/2000
Duration: Four year project to 2004
Contact: Prof. Atkins, Dept of Microbiology, Moyne Institute, Trinity College, Dublin
Project: Elucidating the Role of 1111V6 and MV8 in Multiple Sclerosis and Identifying Novel Genes in MS Pathogenesis
Researcher: Dr. V. Uhlman & Dr. J. J. O'Leary, 1999
Duration: Three year project to 2002
Contact: Prof. John J. O’Leary, Director of Pathology, Coombe Hospital, Dolphins Barn, Dublin
Project: Participation in the project to establish the world’s largest database of MS patient information for statistical analysis of the disease, with the support of the Multiple Sclerosis International Federation (MSIF).
Research: Sylvia Lawry Centre, 2003
Contact: Sylvia Lawry Centre for MS Research, Hohenlindenerstr 1, D-81677 Munich, Germany
Project: Fine Mapping and Assessment of Candidate Genes for 20 loci for MS Susceptibility
Researcher: Dr. Vandenbroeck/Hawkins/Hutchinson, combined project with Drs. Graham / Hawkins/Hutchinson, 2003
Duration: Three Year project
Contact: Dr. Stanley Hawkins, Consultant Neurologist, Institute of Clinical Science, Royal Victoria Hospital, Grosvenor Rd, Belfast BT12
Project: Further Studies on the Molecular and Cellular Basis of Blood – Brain Barrier Injury in MS
Researcher: Dr. Kirk/McQuaid/McConnell, 2003
Duration: Two year project
Contact: Dr. John Kirk, Lecturer in Neuropathology, Queens University, Grosvenor Rd, Belfast BT12 6BL
Project: Continuation of MS in Malta Study
Researcher: Dr. G.K. Dean, 2003
Duration: One year project